•  Anesthetic Anodyne Procaine Hydrochloride CAS 51-05-8
  •  Anesthetic Anodyne Procaine Hydrochloride CAS 51-05-8
  •  Anesthetic Anodyne Procaine Hydrochloride CAS 51-05-8
  •  Anesthetic Anodyne Procaine Hydrochloride CAS 51-05-8
  •  Anesthetic Anodyne Procaine Hydrochloride CAS 51-05-8

Anesthetic Anodyne Procaine Hydrochloride CAS 51-05-8

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CAS:51-05-8

MF:C13H21ClN2O2

MW:272.77

EINECS:200-077-2

Synonyms:aminocaine ;anadolor ;anesthesol ;anestil ;atoxicocaine ;Benzoicacid,4-amino-,2-(diethylamino)ethylester,monohydrochloride ;benzoicacid,p-amino-,2-(diethylamino)ethylester,monohydrochloride ;bernocaine

Properties

Melting point:155-156 °C(lit.)

Boiling point:195-196°C 17mm

Flash point:195-196°C/17mm

storage temp. room temp

form Crystals or Crystalline Powder

color Colorless to white

Water Solubility soluble

Sensitive Air Sensitive

Merck 14,7757

Stability:Stable. Incompatible with strong oxidizing agents.

Safety Information

Symbol(GHS)

 

Description


Procaine HCl (procaine hydrochloride) is the active ingredient in Gerovital H3 (GH3) and in the Vitacels 3 through 8. Procaine HCl is broken down rapidly by enzymes in the blood stream into PABA and DEAE. The PABA and DEAE are rapidly conjugated and removed from the blood and excreted from the body. Because of this procaine HCl and its breakdown products (metabolites) are unable to get into the cells in any great quantity to produce benefits. Procaine HCl will produce some benefits by itself, but they are very limited.


However when procaine HCl is complexed properly (Koch process)(1) the procaine HCl is protected from the action of the enzymes in the blood and tissues this protection gives the procaine enough time to be transfered into the cells of the body where it helps the cells rebuild, repair, and detoxify. This action of the procaine HCl complex is responsible for the remarkable improvements in health that result from the use of GH3 and the Vitacel 3 - 8.

Specification

Product Name

Procaine Hydrochloride

Other Name

4-Aminobenzoic acid 2-(diethylamino)ethyl ester hydrochloride

Assay (%)

≥99.00

Odor

Characteristic

Color

White crystalline powder

Cas No.

51-05-8

Molecular Formula

C13H20N2O2.HCl

Molecular Weight

272.77

Standard

USP34/BP2005


Function

Main functions are as follows:
1.Local anesthetic.

Applications

Main applications are as follows:
Applied in pharmaceuticalfields.

Packing

1kgor 5kg/bag, 25kg/drum

Shelf Life

24 months

Storage

Store in sealed containers at cool & dry place. Protect from light, moisture and pest infestation.

Test Items

Specification

Test Results

Appearance

White crystals or a white crystalline powder

Conform

Identification

ABE. It appears positive reaction

Melting point

154degree~158degree

154degree~157degree

Acidity

PH 5.0~6.5

PH=5.9

Appearance of solution

Clear and colourless

Conform

Loss on drying

≤0.5%

0.07%

Heavy metals

≤0.0005%

Conform

Related substances

≤0.05%

Conform

Sulphated ash

≤0.1%

0.05%

Assay ( on dry basis )

99.0-101.0%

99.87%

Conclusion

Conform to BP2005

 

Application

 

Procaine HCl is a local anesthetic drug of the amino ester group. It is used primarily to reduce the pain of intramuscular injection of penicillin, and it is also used in dentistry. Owing to the ubiquity of the trade name Novocain, in some regions procaine is referred to generically as novocaine. It acts mainly by being a sodium channel blocker.Today it is used therapeutically in some countries due to its sympatholytic, anti-inflammatory, perfusion enhancing, and mood enhancing effects.

Procaine HCl is indicated for the production of local or regional analgesia and anesthesia by local infiltration and peripheral nerve block techniques

 

Anti-painingAnesthetic Anodyne

Name

CAS

Tetracaine hydrochloride

50-41-9

Procaine

59-46-1

Tetracaine

94-24-6

Pramoxine Hydrochloride

637-58-1

Procaine HCl

1951-5-8

Lidocaine

137-58-6

Dibucaine hydrochloride

1961-12-1

prilocaine

721-50-6

Propitocaine hydrochloride

1786-81-8

Proparacaine hydrochloride

5875-6-9

Linocaine hydrochloride

6108-05-0

Articaine hydrochloride

23964-57-0

Levobupivacaine hydrochloride

27262-48-2

Ropivacaine hydrochloride

132112-35-7

Bupivacaine

2180-92-9

Bupivacaine hydrochloride

14252-80-3

 

 

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